Dean's weapon of choice is a stainless and custom engraved .45 caliber Colt MK IV Series 80 1911 pistol with ivory grips, which John is also seen using in a flashback. Dean also uses a Baikal sawed-off, double barrel, break action shotgun when he needs extra firepower. He has also been seen with a H&K G3SG/1 rifle in [[2.05 Simon Said]]. Other small arms used by Dean include a Taurus PT99, a Beretta 92FS, a Smith and Wesson 5906 9x19mm pistol, a Remington 870 12 gauge shotgun and an Ithaca 37 12 gauge shotgun. Dean is shown to possess a large machete in [[1.20 Dead Man's Blood]], and has used a knife in several episodes. Dean has also wielded a Desert Eagle loaded with wrought iron bullets in [[1.18 Something Wicked]] and
tasers which he and Sam used in the start of [[1.12 Faith]], when he electrocuted himself. Dean, along with Sam, John and others, has wielded the Colt, a specially crafted Colt-Patterson model 1836 revolver made by Samuel Colt himself which, with Colt's special bullets, can supposedly kill anything in creation. However, Lucifer mentions that he is one of five things that the Colt cannot kill , it is unknown if the four other entities Lucifer was referring to were God and the three other Archangels (Michael, Gabriel and Raphael) or the Four Horsemen. As with any professional hunter, Dean relies on salt, pure iron and exorcisms to further combat supernatural forces. When firearms and blades are scarce and Dean is in a dangerous situation, he uses a brawling style of hand-to-hand combat or improvised weapons from the surrounding area. During [[4.16 On the Head of a Pin]], Dean is shown with a number of torture implements, including syringes of holy water, although he does not like to resort to these measure unless he has no other choice.