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===[[7.06 Slash Fiction]]===
As [[Bobby]] is testing out various methods to kill the [[Leviathan]] [[Chet]], frustrated that nothing appears to work, Chet begins mocking Bobby telling him how he plans on eating him. Bobby raises his machete, when several drops of a liquid fall from the ceiling onto Chet's arm and burn his skin, causing Chet to panic and plead for Bobby to get it off of him. The skin on Chet's arm turns yellow, then black, and black steam rises. Another drop falls and Chet's arm continues to burn, causing more pain. Another drop falls onto Chet's face is now also burning and a large patch on his arm is black, until Bobby decapitates Chet once more. Bobby rushes upstairs to find the cause of the acidic effect on Chet, to find [[Jody Mills]], who had been scrubbing the floor and knocked over a bucket containing borax in the cleaning solution. With this information, Bobby places a call to [[Dean]] and informs him to use anything with sodium borate -- any soaps or laundry powder with "borax" on the label.
[[Dick Roman]] soon becomes alerted to Sam and Dean's arrival and leaves Bobby in his office while he goes to deal with them. Sam empties his pressure sprayer on Dick, who begins healing faster than the other Leviathans, casually wiping his face with a handkerchief. As he advances on Sam, Dean begins throwing more borax on Dick from behind, causing him to burn, marginally annoying him and allowing for Sam to slip past Dick and make his escape with Dean and Bobby.
===[[7.16 Out with the Old]]===
When confronting [[Joyce Bicklebee]] and her assistant [[George]], in the ensuing fight, Joyce grabs Dean and throws him into a glass cabinet, while George throws Sam over a desk. As Sam tries to defend himself with punches, George grabs Sam around the throat and clues him to the bucket of borax next to them. He tells Sam to dunk his head into it before Joyce sees them talking. Joyce throws Dean onto a table, which breaks as Sam dunks George's head in the bucket. The sight of George's half burned off face, with exposed skull disgusts Joyce, who throws Dean into some glass doors. George alerts Sam to a sword in a display cabinet, and as Joyce advances on Dean, Sam is able to sneak behind her and decapitate Joyce.
===[[7.20 The Girl with the Dungeons and Dragons Tattoo]]===
When [[Charlie Bradbury]] is given [[Frank Devereaux]]'s hard drive to hack, she finds a file on Leviathan's and learns what borax will do to them. After witnessing the Leviathan [[
Terrell]] shapeshift and eat her superior, [[Pete]], Charlie flees to her apartment where she is met by Sam and Dean. To prove to her that they are not Leviathans, they pour borax onto their arms, assuages Charlie's fear when they do not begin to burn. Dean in turn, pours borax on Charlie's hand to prove that she is human.
Learning that Dick is having a package delivered from a excavation site in Iran, and will have 42 minutes to intercept the package at the airport. Sam, Dean and Charlie formulate a plan, and successfully switch out the briefcase with one containing a bottle of Power Clean rigged with explosives, creating a borax bomb. When Dick receives the briefcase and opens it, his look of self-satisfaction quickly turns to confusion as the borax bomb counts down and explodes. The explosion causes a Leviathan bodyguard to have the lower portion of his face to melt, lying prone on the floor, Dick casually walks over him, with burns on his face orders the building locked down. With Charlie trapped in the building Pete begins stomping towards, but is knocked down by Bobby who inadvertently sends him into Charlie, breaking her arm. Sam and Dean proceed to crash through the glass doors, and upon Charlie telling them Pete is a Leviathan, Dean throws a jar of borax into his face, causing him to collapse in pain..