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I was once a son. A younger brother. And I had a brother who I loved. Idolized, in fact. And one day I asked him to stand with me. And he turned on me. Called me a Freak. And he beat me down. <sup>[[5.10 Abandon All Hope]]</sup></blockquote>
[[Gabriel]] draws a clear parallel between Sam and Dean's destiny ("we knew it was all gonna end with you. Always.") and Lucifer and MichealMichael's relationship <sup>[[5.08 Changing Channels]]</sup>
<blockquote> Michael, the big brother, loyal to an absent father, and Lucifer, the little brother, rebellious of Daddy's plan. You were born to this, boys. It's your destiny! It was always you! As it is in heaven, so it must be on earth. One brother has to kill the other.</blockquote>
[[Michael]] tells Dean this is in his bloodline – which is why he can also use [[John Winchester]] as a [[Vessel]].
==[[5.01 Sympathy For The Devil]]==
[[Zachariah]] reveals that the [[Angel]]'s plan is for [[Michael]] to use would use Dean as his [[Vessel]] and kill [[Lucifer]] once and for all. However, dean needs to give his consent to be the [[Vessel]].

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