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{{TriviaQuote |Text=
Emmanuelle Vaugier who plays [[Madison]] in this episode, appeared as Doctor Helen Bryce, Lex Luthors love interest, on the television series[[Smallville] during seasons 2 and 3. Jensen Ackles also starred on [[Smallville]] as Jason Teague in season 4.
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{{TriviaQuote |Text=
Madison's request to Sam to kill her because she doesn't want to live as a [[monster]], closely echoes the plea [[Evil!Sam]] made to Dean in [[2.14 Born Under a Bad Sign]].
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