|Synopsis=
[[Sam]] has been awake for five days, tormented by [[Hallucifer]], who tells Sam he'll only survive another week without sleep. He tries in vain to use drugs to pass out and in his sleep-deprived state, is hit by a car. He winds up in the locked psychiatric ward at [[Northern Indiana State Hospital]], being treated for a broken rib, lacerations , and what the doctors call a full-blown psychotic episode. The doctors have administered several sedatives , but Sam remains conscious.
In the ward, Hallucifer plays cat's cradle and reminds Sam that he didn't need to sleep when he was soulless. Dean arrives and tells Sam he'll find him help. Sam doesn't think he'll be able to find anythingis skeptical, saying they always knew putting his soul back in would end badly. Dean leaves.
At [[Rufus's Cabin]], Dean calls some of [[Bobby |Bobby's]] contacts but is unable to find help. He puts the Bobby's journal on the table and goes to the fridge for a beer. The journal falls to the ground by itself and a card for Mackey's Taxidermy falls out. Dean calls the number and leaves a message.
Hallucifer comments that he and Sam being in a locked ward together is just like the Cage. Sam is eating ignores him and later tries to eat a sandwich , but when he discovers looks at it it is 's full of maggots. He drops it on the ground and backs away while , then notices another patient, Marin, watches watching from his door before leaving. She leaves without saying anything.
At the cabin, Dean is looking for help information online when he receives a call from a hunter named [[Mackey]]. Mackey tells him about a healer named Emmanuel in Colorado. He claims that Emmanuel passed all the of his monster tests and then healed Mackey's his damaged eye with one touch.
Encouraged, Dean goes to Emmanuel's house in Colorado. He meets a man who claims to be Emmanuel at the front door, but sees Emmanuela woman tied up in the house. When he looks back, the man's wife Daphne tied up and fights eyes are black as he shoves Dean into the demon pretending to be Emmanuelfront door. He Dean reminds the demon that about Crowley ordered demons to stay clear of Dean and Sam's "hands-off memo, " but the demon laughs and says that because Dean hasn't killed managed to kill [[Dick Roman]], Crowley will want Emmanuel is more importantthan he wants Dean alive. Dean quickly kills the demon with [[Ruby's knife]]. Just , and then he sees looks up to find Emmanuel, who is the spitting image of [[Castiel]]. Emmanuel doesn't recognise Dean, has no knowledge of demons and no memory of being an angelwatching him.
Emmanuel doesn't recognise Dean, has no knowledge of demons, and no memory of being an angel. He thanks Dean for saving his wife, Daphne, and then says that he saw the real face of the man Dean killed. Dean tells him that it was a demon and that he's there because he needs help for his brother. Meanwhile in the locked ward, the patient who saw Sam's reaction to his sandwich brings him a stolen chocolate bar. Sam thanks her and learns her name, [[Marin]], but can't get further than introductions because Hallucifer is tormenting him with a loudspeaker. Marin leaves, frightened by his strange reactions. Later, Hallucifer continues to torment Sam, lighting firecrackers in the ward. An orderly, Marcus, brings Sam his meal. , and Sam asks Marcus about Marin and he tells . Marcus doesn't tell him much, only that unlike him , she wasn't brought to the psychiatric ward because of an accident.
Dean and Emmanuel talk in the car on the way to Indiana. Emmanuel tells him that Daphne found him by a river, when he wandered into her path "drenched, confused and unclothed", with no memory. Daphne claimed God wanted her to find him. Dean mentions the possibility that Emmanuel was a bad guy, but Emmanuel says he doesn't feel like a bad person.
Marin brings Sam a stolen chocolate bar. She tells him that she hears her dead brother's voice. He wants her to kill herself to be with him, and if she doesn't, he'll do it for her.
Emmanuel tells Dean he can cure illnesses of a spiritual origin and should be able to help Sam. Dean goes on to tell him that he is unable to forgive his friend Cas, who betrayed him and caused Sam's illness. Emmanuel still has no memory and comments that Cas is an odd name.
Dean is confronted by demons at a convenience store. He kills one and another is killed by [[Meg]]. She is there because of rumours about a wandering healer. She has an ongoing feud with [[Crowley]] and doesn't want him to know about Cas. Although she wants to use Cas as a weapon, she agrees not to tell him his true identity yet. The three of them leave together.
Sam and Marin talk about her dead brother. She tells that she hears her dead brother's voice. He wants her to kill herself to be with him how , and if she doesn't, he'll do it for her. How she feels cold before he talks to her, and how one day he got angry and set the room on fire, almost killing her. She says he was cremated, but she wears a bracelet he made for her with an injured hand - it's likely he bled on it. She steals a lighter and makes a ring of salt after Hallucifer blows Sam's ring away. They stand inside the circle and Marin's brother appears. He breaks the lights and pleads with Marin not to do it. She gives Sam the bracelet and he burns it, causing her brother to go up in flames. After Marin thanks Sam and leaves, orderlies enter the ward to restrain Sam. Hallucifer talks over Dr Kadinsky's shoulder as the doc explains to Sam that they cannot give him any more medication and should try surgery instead.
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