|Actor|| Mitch Pileggi|
|Dates||???? – 2011 (killed by Crowley)|
|Episode(s)|| 6.02 Two and a Half Men|
6.10 Caged Heat
The Alpha Shapeshifter was the very first shapeshifter.
The Alpha Shapeshifter is an extremely powerful entity that is the father and leader of all shapeshifters. According to common lore, this Alpha has a connection or bond with its offspring which allows it to locate them.
Powers and abilities
- Regeneration – The Alpha was able to heal itself from all wounds, including being stabbed in the heart with pure silver.
- Super strength and durability – The Alpha's strength greatly exceeded the strength of normal shapeshifters. Its durability and threshold for pain were extremely high. The Alpha showed great resistance to silver, and the only known material that could actually hurt it was iridium.
- Shapeshifting – The Alpha Shapshifter could morph its body to match any human appearance in a matter of seconds. It did not shed or peel while altering its shape. Its shapeshifting extended to being able to morph the clothes it was wearing to whatever the human it was copying was also wearing.
- Telepathy – Like the Alpha Vampire, the Alpha Shapeshifter has a telepathic connection to all his children, allowing it to locate any shapeshifter in the world.
- Animals sensing the paranormal – Dogs have been shown to react aggressively around the presence of shapeshifters.
- The Colt – The Alpha Vampire's death confirmed that Alphas are vulnerable to the Colt.
- Decapitation – Crowley was able to kill the Alpha Shapeshifter through decapitation.
- Iridium – The rare metal burned the Alpha Shapeshifter, similar to the effects of silver on regular shapeshifters and caused excruciating pain.
This shapeshifter starts gathering a following of its "offspring" and is apparently reproducing with women by morphing into their husbands. When Sam and Dean rescue one of its children, the Alpha Shapeshifter storms the Campbell's compound and kills Mark Campbell, overcoming several gunshot wounds and tranquilizer darts, as well as a silver knife to the heart. It then reclaims the baby from Dean and leaves. This shapeshifter is able to transform in just a few seconds without shedding its skin.
Crowley interrogates the Alpha Shapeshifter on Purgatory's location. Crowley then reveals that iridium, although expensive and rare, is capable of damaging and killing the Alpha Shapeshifter. He threatens to kill the shapeshifter's offspring that he currently has captured, but the Alpha Shapeshifter still refuses and tells Crowley that more shapeshifters would be produced if he killed the others. Crowley beheads the Alpha.