|Episode(s)||7.17 The Born-Again Identity|
One day when out hiking, Daphne finds Castiel wet and naked, with no memory of who he is. She claims that God led her to him and takes him home. Using the site bouncingbabynames.com she helps him choose the name Emmanuel. They later marry, and she supports his work as a healer.
Demons have become interested in Emmanuel, and one invades his home, taking Daphne captive. When Dean, he kills the demon, just as "Emmanuel" returns home. He then agrees to go with Dean, and see if he can help Sam. Daphne stays at home.