|Nursery fire||Yes; no deaths|
Rose Holt, or "Rosie," is the baby from 1.21 Salvation. Her parents are Monica Holt and Charlie Holt. The Yellow-Eyed Demon comes to her nursery on her 6 month birthday, as with the other Special Children. Her mother enters the nursery and is attacked, but is saved by Sam and Dean. The nursery is set on fire, and the house burns.
Whether or not the Yellow-Eyed Demon infected Rose is unknown, as are Rose's possible psychic abilities if he did. Her mother says "...she never cries. She just stares at everybody. Sometimes she looks at you and I swear it’s – it’s like she’s reading your mind."