Sasquatch
From Super-wiki
"Sasquatch" is a popular nickname both in the show and in fanfiction to refer to both Sam and Jared. It was also used by the cast and crew and was apparently a nickname of Kim Manners for Jared.(Source)
"Sasquatch" is another name for Bigfoot.
Episodes
2.11 Playthings
When trying to help his drunken brother into bed, Dean calls Sam "Sasquatch" for the first time.
5.12 Swap Meat
When referring to Gary in Sam's body, the motel owner tells Sam (in Gary's body) that two guys checked out of the motel, "One leather jacket, one Sasquatch."
Other
- Jensen Ackles' character, Alec, calls a 6'10" character named Sam "Sasquatch" in episode of Dark Angel.