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From Super-wiki
→Weaknesses: Crowley said that "my [his] tinkering cost several lesser shifters their lives."
* [[Animals sensing the paranormal]] – Dogs have been shown to react aggressively around the presence of shapeshifters.
* Decapitation – Like most things, a shifter can be killed by cutting off it's head.<ref name="six10"/>
* Iridium – The rare metal iridium was shown to be the only thing capable of injuring the [[Alpha Shapeshifter]]. Crowley discovered this while experimenting on other shifters.<ref name="six10">[[6.10 Caged Heat]]</ref>
* [[Retinal flare]]s – Shapeshifters can be identified by the retinal flares they give off on videos.
* [[Silver]] – Piercing the heart with [[silver]] will kill a shapeshifter, while general contact with silver can also cause them harm.<ref name="one06"/><ref name="four05"/><ref name="two12"/>
