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Soul
,→Nature of Souls
When [[Castiel]] rescues [[Sam]] from [[Lucifer's Cage]], his soul remained trapped in the Cage until Death retrieved it for him. Without his soul, [[Sam]] felt no empathy, guilt or compassion. However, he was not evil, but rather lacked any moral compass, and was willing to resort to more questionable actions, such as allowing [[Dean]] to become a [[vampire]] to help them find an [[Alpha]], albeit also knowing that there was a cure for vampirism, than he might consider when normal. While he continued to have physical needs for food and sex, he didn't require sleep, and had a high tolerance for pain. On other occasions that people have lost their souls, they have had different reactions. When souls were stolen by [[Abaddon]]'s demons, they appeared to act on basic instinct with the littlest thing setting them off. As this was different from Soulless Sam, Sam suggests that different people have different reactions to losing their soul.<ref name="nine17">[[9.17 Mother's Little Helper]]</ref> Additionally, [[Amara]]'s soulless victims tended to quickly become homicidal and one noted that it felt like something dark was hatching inside of him.<ref name="eleven05">[[11.05 Thin Lizzie]]</ref><ref name="eleven06">[[11.06 Our Little World]]</ref> In the instance where a soul is forcefully removed, if it is released from whatever is binding it it will return to its body.
After losing his soul, [[Donatello Redfield]] remained mostly the same by using "what would Mr. Rogers do?" as his moral compass.<ref name="thirteen02">[[13.02 The Rising Son]]</ref> The only time this changed was when Donatello was corrupted by the power of the [[tablet|demon tablet]] without his soul there to filter out whatever darkness existed inside of the tablet.<ref name="thirteen14">[[13.14 Good Intentions]]</ref> After being saved from his brain deathis restored by Castiel, Donatello resumed his usual [[soulless]] personality without the corruptionnor any memory of the events during this time.<ref name="fourteen12">[[14.12 Prophet and Loss]]</ref> He would later describe to [[Jack Kline]] having no soul as emptiness: no pity, no empathy, no humanity though he stated that losing your soul doesn't make you anything. He believed that by following the example of the best person you knew in uncertain situations, a soulless person could learn how to live a relatively normal life.<ref name="fourteen15" />
It is possible for a human to use Enochian magic to gain angel-like abilities, but the cost of this is that each time a piece of their soul is burned away until it is completely gone. However, if even a sliver of soul still exists, that sliver will go onto whatever the person's final destination may be.<ref name="twelve10">[[12.10 Lily Sunder Has Some Regrets]]</ref><ref name="fourteen08">[[14.08 Byzantium]]</ref>
[[Anubis]], an Egyptian [[deities|deity]] used as a judge by [[Heaven]] following the departure of [[God]], reveals that a soul's final destination is not chosen by Death, the reapers or even God himself. Instead, a soul's final destination is chosen by the person themselves and their actions in life. Anubis will "weigh" the soul and determine where it will go, though their final destination can be changed by something such as a final selfless sacrificial act.<ref name="fourteen08" />
During his time working with Dumah, it's revealed that Jack can transform humans into angels by forging human souls into angelic grace with ease.<ref name="fourteen19">[[14.19 Jack in the Box]]</ref>
==After Death==
