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→Weapon Properties
The knife has has been used to kill demons, humans, and hellhounds.
The white-eyed demon [[Alastair]] was never killed by the knife's demon killing power since both times he was stabbed were on the left shoulder.<ref name="four09" /><ref name="four16" /> However, [[Sam]] noted at one point that Lilith herself was scared of the knife,<refname="four02">[[4.02 Are You There God? It's Me, Dean Winchester]]</ref> and she continually took precautions to avoid being stabbed with it whenever confronted with it.<refname="three16">[[3.16 No Rest for the Wicked]]</ref><refname="four18">[[4.18 The Monster at the End of This Book]]</ref>
[[Crowley]], too, has always avoided being stabbed with the knife.<refname="five20">[[5.20 The Devil You Know]]</ref><refname="six10">[[6.10 Caged Heat]]</ref> While Crowley stated in that the knife couldn't kill him <ref name="ten22">[[10.22 The Prisoner]] that the knife couldn't kill him</ref>, this may have been a bluff as he was later shown to be nervous in its presence when Dean pulled it on him after disabling him with an [[angel blade]].<refname="eleven02">[[11.02 Form and Void]]</ref> Dean was later able to disable Crowley for a time by impaling the knife through his hand,<ref name="twelve23">[[12.23 All Along the Watchtower]]</ref> but Crowley eventually escaped somehow like he'd escaped a similar injury from an angel blade.<ref name="eleven02" /> After freeing himself, Crowley apparently retained the hand wound as he kept the hand that was stabbed wrapped up in a bandage.<ref name="twelve23" />
When [[Abaddon]] was stabbed by the blade, she survives despite experiencing intense pain, revealing that the [[Knights of Hell]] are partially immune to its demon killing abilities.<refname="eight12">[[8.12 As Time Goes By]]</ref> Unlike Abaddon, [[Cain]] stabs himself with the blade after Dean threatens him and suffers no pain or even any sign of exsanguination.<refname="nine11">[[9.11 First Born]]</ref>
After surviving a killing blow from the knife by Sam, it was revealed that [[Ramiel]] and all [[Princes of Hell]] are immune to the knife's power.<refname="twelve12">[[12.12 Stuck in the Middle (With You)]]</ref>
==Episodes==