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When [[Abaddon]] was stabbed by the blade, she survives despite experiencing intense pain, revealing that the [[Knights of Hell]] are partially immune to its demon killing abilities.<ref name="eight12" /> Unlike Abaddon, [[Cain]] stabs himself with the blade after Dean threatens him and suffers no pain or even any sign of exsanguination.<ref name="nine11" />
After surviving a killing blow from the knife by Sam, it was revealed that [[Ramiel]] and all [[Princes of Hell]] are immune to the knife's powerthough like Abaddon, the knife caused Ramiel some pain.<ref name="twelve12" />
==Episodes==