The Antichrist is the only one who could match Michael's true power. Jesse was said to be able to destroy the host of heaven (Michael) with just a word. Not even Lucifer could kill Michael. It could be speculated that Lucifer is in fact afraid of Michael because of his power. -who ever wrote this please only give information given by the show or creators and if you did please provide a link to where. OldNick666
The part about Michael not being affected by Enochian should be removed. He could have set up the entire Anna vs. Sam and Dean situation by letting Anna out. He could also easily find John and Mary, who didn't have sigils on their ribs.